Pharma / Mastersheets
Transform Excel spreadsheets into secure, GxP-compliant assets with cell-level audit trails, locked formulas, and 21 CFR Part 11 signatures.
The problem
Using spreadsheets like Excel™ for critical GxP calculations carries severe non-compliance risks due to limited data protection, poor access control, and the complexity of maintaining a single validated copy—leaving organizations vulnerable to regulatory scrutiny.
The solution
Mastersheets is a web-based spreadsheet platform fully compliant with regulatory standards from the FDA, MHRA, and global health authorities. It unifies GxP calculations into secure, centralized storage with granular access control, cell-level audit trails, and configurable approval workflows—eliminating compliance risks while preserving the familiar ease of spreadsheets.
Maintain a single source of truth for all validated templates and digitally signed spreadsheets.
Restrict editing and viewing rights to authorized personnel across every file.
Capture every cell modification and calculation change with an immutable, signed history.
Enforce multi-tier review and approval processes aligned directly with your SOPs.
Restrict platform entry to authorized personnel through secure, password-controlled user authentication and credential policies.
Control exactly what users can do within each sheet—defining custom roles to create, review, execute, or approve calculation workflows.
Lock proprietary formulas and analytical logic permanently, opening only designated input cells for analysts to enter verified data.
See how Mastersheets locks formulas, signs records and keeps every cell change on the audit trail.